Váltás magyarra (Change to Hungarian)

    FRIGYES, DÁVID

Eötvös Loránd University Physical Organometallic Chemistry Lab. e-mail: frigyes(at)elte.hu

• Ph.D. Inorganic and Theoretical Chemistry, Eötvös Loránd University, 2002. (Thesis in Hungarian)
• M.Sc. Chemistry, Eötvös Loránd University, 1995.



• Senior Development analyst, EGIS Pharmaceutical PLC, 2009-
• Study Director, AIDR Auricoop Nonprofit Llc 2008-2009
• Associated Member of Physical Inorganic Laboratory, Eötvös Loránd University, 2006-
• Assistant Professor, Eötvös Loránd University, 2004-2008
• Teaching Assistant, Eötvös Loránd University, 1999-2004

Current research

• Quantitative analysis of (potentially) genotoxic impurities of API's (Active Pharmaceutical Ingredients)

Research experience

• Mass spectrometry: Characterization of organic (heterocyclic, organofluorine componds etc.) and organometallic/organometalloid compounds (ferrocene derivatives, transition metal carbonyl, chalcocarbonyl, dinitrogen and isocyanide complexes, organosilicon, -tin and -bismuth compounds etc.) using electron impact (EI)-mass spectrometry
• Analytical chemistry: determination of plant volatile compounds using solid phase microextraction gas chromatography mass spectrometry (SPME/GCMS)
• Synthetic organometallic chemistry: preparations of main group and transition metal-organic compounds using inert athmosphere techniques
• Photoelectron spectroscopy (PES): Characterization of the electronic structure of stable and transient organometallic compounds. gas-phase reactions. electronic structure - activity relationships in organometallic compounds  
• Quantum Chemistry: ab initio quantum chemistry and molecular dynamics (Car-Parrinello) of transition metal complexes and their reactions.

Studies abroad

• 1996-97: Soros Foundation-grant: CNR, Bologna, Italy: Examinations of treated Si <100> and <111> surfaces using Scanning Tunneling Microscopy
• 1999-2000: ICGEB-grant: ICGEB, Trieste, Italy: Ab initio molecular dynamics investigation of Protein-DNA complexes

Teaching Activities

• Laboratory Courses
  • General Chemistry Laboratory Course: for 1st-year chemistry students
  • Inorganic Chemistry Laboratory Course: for 1st-year chemistry students
  • Inorganic and Organometallic Laboratory Course: for 3rd-year chemistry students
  • Graduate structure determining laboratory course: for 4th-year students: Photoelectron spectroscopy; mass spectroscopy
• Lectures
  • Mass Spectrometry(with Kálmán Újszászy and Károly Vékey):
  • Vacuum technology (with István P. Csonka)
  • Structural Chemistry(corresponding lecturer: Pál Sohár): Compulsory course for 3rd-year chemistry students. The basics of mass spectrometry: the instrumental set-up, origin of the fragmentation: simple cleavages, rearrangements, characteristic fragmentation patterns of specific functional groups 2000-2005
• Other courses

Publications

• Papers in International journals
• Conference abstracts
  1. Frigyes, D., Csonka, I., Szepes, L., Investigation of s-allyl(R)p -allyl rearrangements in Mn and Re complexes using He(I) photoelectron spectroscopy, Abstracts of the XIth FECHEM Conference on Organometallic Chemistry, Parma, Italy, 1995, p. 130
  2. Csonka I., Frigyes D., Vass G., Kapovits I., Szepes L., He(II) sugárforrással szerzett tapasztalatok szerves kénvegyületek UV fotoelektron-spektroszkópiás vizsgálatánál, 39. Magyar Spektrokémiai Vándorgyűlés kiadványa, Mosonmagyaróvár, 1996. szeptember 4-6., 203
  3. Frigyes, D., Szepes, L., Electronic and Molecular Structure of Manganese Pentacarbonyl Hydride and Manganese Tetracarbonyl Hydride: An ab initio Quantumchemical Study, XIIth FECHEM Conference on Organometallic Chemistry, August 31-September 5, 1997, Prague, Book of Abstracts, PA176.
  4. D. Frigyes, P. Carloni, Protein–DNA complexes: an ab initio Molecular Dynamics Study, Workshop on Calculation of Material Properties using Total Energy and Force Methods and ab initio molecular dynamics, 9–18 August, 1999, Trieste, Italy.
  5. O. Ozohanics, V. Zsoldos-Mády, J. Pásztor, A. Csámpai, D. Frigyes, P. Sohár, Synthesis of new ferrocenyl heterocycles containing sugar moiety, 2nd Austrian-Hungarian Carbohydrate Symposium, Somogyaszaló, 2005 May 24-26, Somogyaszaló, Hungary
  6. I. P. Csonka, D. Frigyes, Electron impact mass spectroscopic investigation of transition metal isocyanide complexes, 25th Informal Meeting on Mass Spectrometry, 2007 May 6-10, Nyíregyháza–Sóstó, Hungary
  7. K. Rádi , Cs. Peltz, K.Újszászy, D. Frigyes, Investigation of the effects contributing to response factors in gas chromatography–electron impact–mass spectrometry, 25th Informal Meeting on Mass Spectrometry, 2007 May 6-10, Nyíregyháza–Sóstó, Hungary
  8. M. Pátfalusi, Gy. Somorjai, V. Piryatinsky, D. Frigyes, In vivo and in vitro metabolite profile by LC/MS methods, Conference on pharmacokinetics and metabolism, 2010 Apr 14-16, Galyatetż, Hungary
  9. Gyenge Zsuzsa, Szoboszlai Norbert, Frigyes Dávid, Barkács Katalin, Záray Gyula, Mihucz Viktor Gábor: Metamizol metabolitok koncentrációjának monitorozása magyarországi szennyvizekben, Második Környezetkémiai Szaminárium, Dobogókż, 2013, október 10-11.

Society memberships

• MKE Mass Spectrometry Society (member of the board)
• member of public body of Hungarian Academy of Sciences

Last modified: 27 March 2010